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Zika virus and assisted reproduction
Christina N Cordeiro1, Rashda Bano, Chantel I Washington Cross
1aJohns Hopkins University School of Medicine, Baltimore, Maryland, USA bSpeciality Doctor in EFREC (Edinburgh Fertility & Reproductive Endocrine Centre), Edinburgh, United Kingdom.
Current Opinion in Obstetrics & Gynecology
|April 15, 2017
Summary
Zika virus poses a risk in assisted reproduction due to sexual transmission. Recommendations include waiting periods for infected individuals and tissue donors to prevent disease spread.
Area of Science:
- Reproductive medicine
- Infectious diseases
- Virology
Background:
- Zika virus is a sexually transmitted pathogen.
- Transmission poses risks during assisted reproductive technology (ART).
- This presents challenges for fertility treatments.
Purpose of the Study:
- To review Zika virus sexual transmission.
- To correlate findings with ART recommendations.
- To address concerns for couples undergoing fertility treatment.
Main Methods:
- Literature review of Zika virus transmission.
- Analysis of current recommendations for infertility treatment.
- Correlation of viral shedding data with ART protocols.
Main Results:
- Zika virus RNA detected in blood, semen, cervical, and vaginal fluids.
- Sexual transmission confirmed via vaginal, oral, and anal intercourse.
- CDC recommends 6-month wait for infected men, 8 weeks for women, and 6 months for tissue donors.
Conclusions:
- Further research on Zika virus in reproductive tissues is essential.
- Validated testing methods for viral transmissibility are needed.
- ART protocols must incorporate screening and testing to mitigate Zika virus transmission risk.