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Updated: Aug 8, 2026
Measurement of Chitinase Activity in Biological Samples
Published on: August 22, 2019
Antiageing activities of water-soluble chitosan from Clanis bilineata larvae
Shengjun Wu1, Mingsheng Lu1, Shujun Wang1
1School of Marine Life and Fisheries, Huaihai Institute of Technology, 59 Cangwu Road, Xinpu, 222005, China; Co-Innovation Center of Jiangsu Marine Bio-industry Technology, Huaihai Institute of Technology, Lianyungang, 222005, China; Jiangsu Marine Resources Development Research Institute, Huaihai Institute of Technology, Lianyungang, 222005, China.
Abstract:
Water extracts were prepared using water-soluble chitosan from Clanis bilineata larva skin. This study also investigated antioxidant and antiageing activities of water-soluble chitosan. Water-soluble chitosan of Clanis bilineata larva skin (CBLSWSC) showed considerable scavenging activities on superoxide anion and hydroxyl radicals and reducing capacity. Different doses of CBLSWSC were intragastrically administered on a d-galactose-induced-aged mouse model over a period of six weeks. Intragastric CBLSWSC administration significantly increased activities of superoxide dismutase and glutathione peroxidase and inhibited formation of malondialdehyde in brains and sera of mice in a dose-dependent manner. Results suggest that CBLSWSC exhibits high antioxidant activity and can be developed as potential dietary supplement to retard ageing in humans.
