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Immunological conservation between Epstein-Barr virus and herpes simplex virus
E Littler1, I W Halliburton, K L Powell
1Paterson Institute for Cancer Research, Christie Hospital and Holt Radium Institute, Manchester, U.K.
The Journal of General Virology
|August 1, 1988
Abstract:
We have analysed Epstein-Barr virus (EBV)- and herpes simplex virus (HSV)-infected cells for evidence of antigenic conservation of virus-coded proteins. Immunofluorescence and Western blot analyses of EBV-transformed cell lines demonstrated the presence of proteins that are antigenically related to the HSV alkaline DNase, infected cell-specific protein 34/35, glycoprotein B, thymidine kinase and the major DNA-binding protein. These proteins were characterized on the basis of Mr and possible kinetic class.