Role of cellulose functionality in bio-inspired synthesis of nano bioactive glass

In search of abundant cheaper natural polymer for bio-inspired bioactive glass nanoparticles synthesis, cellulose and its derivatives have been considered as a template. Different templates explored in the present studies are pure cellulose, methyl cellulose and amine grafted cellulose. To the best of our knowledge, for the first time of the considered templates, pure cellulose and amine grafted cellulose results in in situ nano particulate composite formation while interestingly methyl cellulose proves to be an excellent sacrificial template for the synthesis of uniform bioglass nanoparticles of diameter in the range of 55nm. Further, viscoelastic measurements were carried out using dynamic mechanical analyzer. Herein, an attempt has been made to establish structure-mechanical relationship based on the templates. Moreover, in vitro bioactivity is also observed to be affected by the nature of the template molecule used for the synthesis of bioactive glass.