Related Experiment Video
Updated: Aug 14, 2026

Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
Birth weight, biological maturation and obesity in adolescents: a mediation analysis
A O Werneck1, D R P Silva1, P J Collings2
11Study and Research Group in Metabolism, Nutrition, and Exercise - GEPEMENE,State University of Londrina - UEL,Londrina,Brazil.
Abstract:
This study was aimed to investigate associations between birth weight and multiple adiposity indicators in youth, and to examine potential mediating effects by biological maturation. This was a school-based study involving 981 Brazilian adolescents aged between 10 and 17 years. Birth weight was reported retrospectively by mothers. Maturation was estimated by age of peak height velocity. Adiposity indicators included body mass index (BMI), waist circumference and percent body fat estimated from triceps and subscapular skinfolds. Multilevel mediation analyses were performed using the Sobel test, adjusted for chronological age, gestational age, cardiorespiratory fitness and socio-economic status. Except for body fat in girls, biological maturation partly or fully mediated (P<0.05) positive relationships between birth weight with all other obesity indicators in both sexes with their respective values of indirect effects with 95% confidence intervals: BMI [boys: 0.44 (0.06-0.82); girls: 0.38 (0.13-0.64)], waist circumference [boys: 1.14 (0.22-2.05); girls: 0.87 (0.26-1.48)] and body fat [boys: 0.60 (0.13-1.07)]. To conclude, birth weight is associated with elevated obesity risk in adolescence and biological maturation seems to at least partly mediate this relationship.
More Related Videos
Related Concept Videos
Nature and Nurture
Regression Toward the Mean
Obesity
Cognitive Development During Adolescence
Influence of Parents and Peers on Identity
Parental Influence on Identity Development
Parents serve as primary guides and managers in an adolescent's life, offering support instrumental in decision-making and personal growth. This guiding role...
Sources of Self-Esteem I: Family Experience

