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Related Experiment Videos

Intrusions in episodic memory: reconsolidation or interference?

Angela Klingmüller1, Jeremy B Caplan1,2, Tobias Sommer1

  • 1Department for Systems Neuroscience, Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

Learning & Memory (Cold Spring Harbor, N.Y.)
|April 19, 2017
PubMed
Summary

Reconsolidation research may not apply to human episodic memory. Findings suggest cognitive effects like interference, not memory destabilization, explain intrusion rates in memory recall tasks.

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Area of Science:

  • Cognitive Psychology
  • Neuroscience
  • Memory Research

Background:

  • Reconsolidation is crucial in animal memory research.
  • Generalizing reconsolidation to human episodic memory remains unclear.
  • Previous studies suggested a specific procedure demonstrated human episodic memory reconsolidation.

Purpose of the Study:

  • To replicate findings of high intrusion rates in episodic memory recall.
  • To evaluate the reconsolidation account against an alternative cognitive account.
  • To test the assumption of memory reactivation and destabilization in reconsolidation.

Main Methods:

  • Utilized a 3-d-list-discrimination procedure with free recall and contextual cues.
  • Conducted replication attempts (Experiment 1) and variations with salient contexts (Experiment 2).

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  • Investigated memory reactivation and destabilization during context re-exposure (Experiment 3).

    • Main Results:

    • Replication of high intrusion rates was not straightforward.
    • A qualitative but small replication was observed with a highly salient context.
    • Evidence supporting memory reactivation and destabilization for reconsolidation was not found.

    Conclusions:

    • The reconsolidation account for human episodic memory requires further evidence.
    • Findings are better explained by established cognitive effects like item-to-context binding and interference.
    • The study challenges the necessity of additional neurobiological processes for memory destabilization in this context.