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Severe MRSA Enterocolitis Caused by a Strain Harboring Enterotoxins D, G, and I
Emerging Infectious Diseases
|April 19, 2017
Abstract:
We describe a case of methicillin-resistant Staphylococcus aureus (MRSA) enterocolitis in a healthy adult with previous antibiotic exposure. Colonoscopy revealed diffuse colitis and mild ileitis without ulceration. Stool cultures demonstrated abundant growth of MRSA and absent normal flora. Oral vancomycin treatment was effective and seems to be the consensus choice for therapy.
Insights
Methicillin-resistant Staphylococcus aureus (MRSA) enterocolitis occurred in a healthy adult after antibiotic use. Oral vancomycin effectively treated this MRSA infection, highlighting its therapeutic role.
Area of Science:
- Infectious Diseases
- Gastroenterology
- Microbiology
Background:
- Antibiotic exposure is a known risk factor for Clostridioides difficile infection.
- Emerging antibiotic-resistant organisms, such as MRSA, can cause gastrointestinal infections.
Observation:
- A healthy adult presented with symptoms of enterocolitis following recent antibiotic treatment.
- Colonoscopy showed diffuse colitis and mild ileitis, but no ulcerations.
- Stool analysis revealed significant MRSA growth and a lack of normal gut flora.
Findings:
- The patient was diagnosed with methicillin-resistant Staphylococcus aureus (MRSA) enterocolitis.
- Oral vancomycin was administered as the treatment for MRSA enterocolitis.
- The patient showed a positive response to vancomycin therapy.
Implications:
- This case underscores the potential for MRSA to cause enterocolitis in previously healthy individuals.
- Oral vancomycin appears to be a viable and effective treatment option for MRSA enterocolitis.
- Further research into non-C. difficile antibiotic-associated colitis is warranted.