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A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
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Transcriptome sequencing study implicates immune-related genes differentially expressed in schizophrenia: new data

A R Sanders1,2, E I Drigalenko3, J Duan1,2

  • 1Department of Psychiatry and Behavioral Sciences, NorthShore University HealthSystem, Evanston, IL, USA.

Translational Psychiatry
|April 19, 2017
PubMed
Summary

This study identified 1058 differentially expressed genes in schizophrenia cases using RNA sequencing, with many linked to immune function. Findings were validated by a meta-analysis combining RNA sequencing and array data, reinforcing immune system involvement in schizophrenia.

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