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Published on: March 15, 2017
Four New Diterpene Glucosides from Perovskia atriplicifolia
Lu Gao1,2, Jun Zhou2, Le-Yu Zhu2
1College of Life & Environmental Sciences, Minzu University of China, Beijing, 100081, P. R. China.
Abstract:
Four new diterpene glucosides, namely perovskiaditerpenosides A - D (1 - 4), were isolated from the BuOH extract of Perovskia atriplicifolia. Their structures were well elucidated by chemical methods and comprehensive spectroscopic analyses including MS, IR, and NMR (1D and 2D). The newly isolated compounds were screened for their cytotoxic activity against HepG2, NB4, HeLa, K562, MCF7, PC3, and HL60. The obtained results indicated that the new compounds possessed considerable cytotoxic activity.
