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Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing
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Intersect-then-combine approach: improving the performance of somatic variant calling in whole exome sequencing data

Maurizio Callari1, Stephen-John Sammut1, Leticia De Mattos-Arruda1

  • 1CRUK Cambridge Institute, University of Cambridge, Cambridge, UK.

Genome Medicine
|April 20, 2017
PubMed

Keywords:
BWAFilteringMutect2NA12878NovoalignPlatinum genomeSomatic mutationStrelkaVariant callingWhole exome sequencing

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