Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cytomegalovirus infection.

M A Jacobson1, J Mills

  • 1University of California, San Francisco.

Clinics in Chest Medicine
|September 1, 1988
PubMed
Summary

Cytomegalovirus (CMV) significance in AIDS-related pneumonia is unclear. While CMV co-infection may indicate poor outcomes in Pneumocystis pneumonia, definitive CMV lung disease is rare in AIDS patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

SARMs, Metabolic Modulators and Growth Hormone Secretagogues in Suspected Illegal Medicines, Bought as Sport Performance Enhancers: A Retro- and Prospective Study Within the GEON.

Drug testing and analysis·2025
Same author

First Measurement of η Meson Production in Neutrino Interactions on Argon with MicroBooNE.

Physical review letters·2024
Same author

First Double-Differential Measurement of Kinematic Imbalance in Neutrino Interactions with the MicroBooNE Detector.

Physical review letters·2023
Same author

First Measurement of Quasielastic Λ Baryon Production in Muon Antineutrino Interactions in the MicroBooNE Detector.

Physical review letters·2023
Same author

The fast camera (Fastcam) imaging diagnostic systems on the DIII-D tokamak.

The Review of scientific instruments·2023
Same author

First Constraints on Light Sterile Neutrino Oscillations from Combined Appearance and Disappearance Searches with the MicroBooNE Detector.

Physical review letters·2023

Area of Science:

  • Infectious Diseases
  • Pulmonology
  • Virology

Background:

  • The role of cytomegalovirus (CMV) in acquired immunodeficiency syndrome (AIDS)-associated pneumonitis remains debated.
  • Distinguishing CMV infection from CMV disease and managing frequent co-infections with other pathogens complicate assessments.

Purpose of the Study:

  • To clarify the pathogenic significance of CMV in AIDS-associated pneumonitis.
  • To define criteria for initiating ganciclovir therapy in relevant cases.

Main Methods:

  • Literature review of reported cases of CMV in AIDS patients with pulmonary symptoms.
  • Analysis of studies examining CMV co-infection in Pneumocystis carinii pneumonia.

Main Results:

  • Few cases (three identified) show definitive CMV cytopathic effect in lung tissue without other opportunistic pathogens in AIDS patients with hypoxemia and infiltrates.
  • Pulmonary CMV co-infection may serve as a prognostic marker for poor outcomes in Pneumocystis carinii pneumonia.

Conclusions:

  • Evidence for CMV as a primary cause of pneumonitis in AIDS is limited.
  • Criteria for ganciclovir treatment initiation in suspected CMV lung disease are discussed.

Related Experiment Videos