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Related Experiment Videos

Do Modic changes affect cervical sagittal alignment and motion in symptomatic patients?

Tong Tong1, Xian-Da Gao1, Jia Li1

  • 1Department of Orthopaedic Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050000, Hebei, China.

European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
|April 20, 2017
PubMed
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Modic changes (MCs) in the cervical spine are linked to increased cervical instability, reduced curvature, and limited range of motion (ROM). These findings suggest MCs may indicate a higher risk for these related spinal conditions.

Area of Science:

  • Spine diagnostics
  • Radiology
  • Orthopedics

Background:

  • Modic changes (MCs) and cervical segmental instability often coexist.
  • The relationship between MCs and cervical spine biomechanics remains unclear.

Purpose of the Study:

  • To investigate the association between Modic changes (MCs) and cervical segmental instability.
  • To evaluate the relationship between MCs, cervical curvature, and range of motion (ROM).

Main Methods:

  • Retrospective analysis of 464 patients with neck pain or neurological symptoms.
  • Diagnosis of cervical MCs via MRI; comparison of instability, curvature, and ROM between groups.
  • Logistic regression analysis to identify risk factors for MCs.

Main Results:

Keywords:
Cervical instabilityMagnetic resonance imagingModic changesRange of motionSagittal alignment

Related Experiment Videos

  • MCs were found in 94/464 patients, most common at C5-C6.
  • Significantly higher incidence of cervical instability in patients with MCs (C3-C7).
  • Patients with MCs exhibited reduced cervical curvature and ROM compared to those without MCs.

Conclusions:

  • Cervical spine instability, reduced curvature, and ROM are identified as risk factors for Modic changes.
  • Patients with MCs show a predisposition to cervical instability and may have poorer cervical biomechanics.