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Related Experiment Videos

Lactase Non-persistence and Lactose Intolerance.

Theodore M Bayless1,2, Elizabeth Brown3, David M Paige3

  • 1Meyerhoff Digestive Diseases-Inflammatory Bowel Disease Center, Gastroenterology Division, Johns Hopkins University School of Medicine, Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MD, 21287, USA. tbayless@jhmi.edu.

Current Gastroenterology Reports
|April 20, 2017
PubMed
Summary
This summary is machine-generated.

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Lactase non-persistence affects most adults globally, impacting milk consumption. Strategies focus on managing lactose intolerance through diet and modified dairy products to ensure nutrient intake.

Area of Science:

  • Nutritional Science
  • Human Genetics

Background:

  • Genetically determined lactase non-persistence affects 65-70% of the global adult population.
  • Lactose intolerance is a significant factor influencing milk consumption patterns worldwide.

Purpose of the Study:

  • To evaluate the clinical and nutritional significance of lactase non-persistence.
  • To assess the impact of lactose intolerance on milk consumption and nutrient intake.

Main Methods:

  • Review of existing literature on lactase non-persistence and milk consumption.
  • Analysis of factors influencing milk intake in populations with high lactase non-persistence prevalence.

Main Results:

  • Milk consumption is lowest in regions with high lactase non-persistence.
Keywords:
Evolution, positive selectionLactase non-persistenceLactase persistenceLactose intoleranceMilk drinking

Related Experiment Videos

  • Some individuals with lactose intolerance can tolerate milk with meals, especially without IBS.
  • Lactase persistence is linked to survival advantages in specific populations.
  • Dairy industry and researchers are developing strategies to mitigate lactose intolerance's impact.

    • Conclusions:

    • Efforts to improve calcium and Vitamin D intake involve promoting consumption of tolerable milk amounts with meals.
    • Lowered lactose-content foods like hard cheeses, yogurt, and hydrolyzed milk are recommended.
    • Managing lactose intolerance is key to maintaining adequate nutrient intake in a large portion of the world's population.