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Chapter 20 Gavi-Automated Vitrification Instrument.

Tammie K Roy1, Susanna Brandi2, Teija T Peura2

  • 1, Genea Biomedx, Level 2, 321 Kent St, Sydney, NSW, Australia. tammie.roy@geneabiomedx.com.

Methods in Molecular Biology (Clifton, N.J.)
|April 20, 2017
PubMed
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Gavi automates oocyte and embryo cryopreservation by standardizing vitrification equilibration steps. This closed-system approach minimizes variability and reduces errors in laboratory and clinical settings.

Area of Science:

  • Reproductive biology
  • Cryobiology
  • Biotechnology

Background:

  • Cryopreservation of human oocytes and embryos is crucial for assisted reproductive technologies.
  • Vitrification is a common cryopreservation method, but it is sensitive to procedural variability.
  • Manual equilibration steps can introduce inconsistencies, potentially affecting outcomes.

Purpose of the Study:

  • To introduce Gavi, an automated system for oocyte and embryo vitrification.
  • To reduce variability in the equilibration process during cryopreservation.
  • To enhance the standardization and repeatability of vitrification procedures.

Main Methods:

  • Gavi automates the equilibration stages of the vitrification process.
  • The system operates in a controlled, closed-system environment.
Keywords:
AutomationCryopreservationEmbryoGaviIVFStandardizationVitrification

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  • It is designed for use with oocytes, cleavage-stage embryos, and blastocysts.

    • Main Results:

    • Automated equilibration minimizes procedural variability.
    • Reduces the potential for human error during vitrification.
    • Ensures a standardized and repeatable cryopreservation procedure.

    Conclusions:

    • Gavi offers a standardized and reliable method for oocyte and embryo vitrification.
    • The automated system enhances the safety and efficacy of cryopreservation.
    • It is suitable for both laboratory and clinical applications in reproductive medicine.