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[AGED CARDIOHEMODYNAMICS COMPLICATED BY STROKE].

V P Nesterov1,2, M F Ballyzek3, A O Konradi2

  • 1Sechenov Institute of Evolutionary Physiology and Biochemistry of RAS, Saint-Petersburg, Russian Federation; nesterov@iephb.ru.

Advances in Gerontology = Uspekhi Gerontologii
|April 20, 2017
PubMed
Summary
This summary is machine-generated.

Arterial piezopulsometry reveals age-related hemodynamic changes post-stroke. Increased pulse pressure and wave velocity in the affected arm indicate functional status and recovery during rehabilitation.

Keywords:
augmentation index pulse pressurecardiohemodynamicsischemic strokepiezopulsometrywave velocity of propagation through the arteries

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Area of Science:

  • Cardiovascular Physiology
  • Gerontology
  • Rehabilitation Medicine

Background:

  • Ischemic stroke significantly impacts cardiac hemodynamics and aging.
  • Assessing age-related cardiovascular changes is crucial for stroke recovery.
  • Objective markers for monitoring functional recovery are needed.

Purpose of the Study:

  • To investigate age-related hemodynamic changes after ischemic stroke using arterial piezopulsometry.
  • To establish prognostic criteria for resistance to aging and cardiovascular pathology.
  • To identify objective indicators of functional status and recovery in paralyzed limbs.

Main Methods:

  • A 12-year study utilizing a novel arterial piezopulsometry technique.
  • Simultaneous dual registration of piezopulsograms from both arms.
  • Analysis of cardiac hemodynamic indices, including augmentation index of pulse pressure (AIxPP) and pulse wave velocity (Var).

Main Results:

  • Significant increase in AIxPP and Var observed in the paralyzed right arm compared to the left arm (p < 0.05).
  • Fluctuations in the difference of these indices correlate with the functional state during rehabilitation.
  • A sharp decrease and stabilization of this difference indicate the onset of recovery.

Conclusions:

  • Arterial piezopulsometry provides valuable prognostic criteria for cardiovascular health and aging resistance post-stroke.
  • AIxPP and Var differences serve as objective indicators for monitoring paralyzed limb function and rehabilitation progress.
  • This method offers a non-invasive approach to assess recovery trajectories after ischemic stroke.