[ADVANCED AND SENILE AGE FOR THE FIRST DAYS AFTER X-RAY ENDOVASCULAR INTERVENTIONS]

Area of Science:

• Cardiology
• Nephrology
• Radiology

Background:

• X-ray endovascular interventions are common procedures in patients with ischemic heart disease.
• Assessing renal function, specifically glomerular filtration rate (GFR), is crucial in elderly patients undergoing such procedures.
• Age-related decline in GFR can be exacerbated by medical interventions.

Purpose of the Study:

• To evaluate changes in glomerular filtration rate (GFR) in patients of advanced and senile age following X-ray endovascular interventions.
• To compare different methods for screening GFR calculations in these patient groups.
• To determine the most suitable formula for GFR screening in elderly individuals undergoing coronary angiography.

Main Methods:

• Retrospective analysis of patients undergoing X-ray endovascular interventions.
• Categorization of patients into age groups: 34-59 years (control), 60-74 years, and 75-82 years.
• Comparison of screening calculation methods for glomerular filtration rate (GFR).

Main Results:

• A decrease in GFR was observed in all patient groups after coronary angiography, irrespective of the initial GFR level.
• The decline in GFR was more pronounced in the senile age group (75-82 years).
• The Cockcroft-Gault formula demonstrated utility for screening GFR determination in elderly patients.

Conclusions:

• X-ray endovascular interventions, specifically coronary angiography, lead to a reduction in GFR in elderly patients.
• Senile age is associated with a greater GFR decline post-intervention.
• The Cockcroft-Gault formula is recommended for screening GFR assessment in advanced and senile age groups undergoing X-ray endovascular interventions, particularly for those with ischemic heart disease.