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Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)
Published on: September 14, 2010
Disseminated warts and evolving squamous cell carcinoma in a patient with acquired immunodeficiency syndrome
P B Milburn1, J L Brandsma, C I Goldsman
1Department of Dermatology, State University of New York Health Science Center, Brooklyn 1203-2098.
Abstract:
A patient with acquired immunodeficiency syndrome developed widespread verrucous lesions on the hands, feet, and penis. Histologic analysis revealed typical changes of verruca vulgaris and, from several sites, a transformation toward squamous cell carcinoma. Southern blot analysis of deoxyribonucleic acid from penile wart tissue indicated the presence of a type of human papillomavirus that rarely is associated with carcinoma.
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