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Bilateral pallidotomy for Meige syndrome
Krasimir Minkin1, Kaloyan Gabrovski2, Petia Dimova2
1Functional Neurosurgery Unit, Department of Neurosurgery, University Hospital "Saint Ivan Rilski", Sofia, Bulgaria. minkin@abv.bg.
Acta Neurochirurgica
|April 21, 2017
Summary
This study presents the first case of staged bilateral pallidotomy (PT) for Meige syndrome (MS), a movement disorder. The procedure significantly improved dystonia symptoms with no adverse neurological effects.
Area of Science:
- Neurology
- Neurosurgery
- Movement Disorders
Background:
- Meige syndrome (MS) involves blepharospasm and oromandibular dystonia.
- Deep brain stimulation (DBS) of the globus pallidus internus (GPI) is reported for MS.
- Only one prior report exists for unilateral pallidotomy (PT) in MS.
Observation:
- This study details the first case of staged bilateral pallidotomy (PT) for Meige syndrome.
- Intraoperative high-frequency stimulation was used to predict and prevent postoperative deficits.
- The patient experienced significant improvement in dystonia symptoms.
Findings:
- A significant reduction in the Burk-Fahn-Marsden dystonia rating scale score from 26 to 3 was observed.
- No adverse neurological or neuropsychological events occurred postoperatively.
- Staged bilateral PT is a viable treatment option for Meige syndrome.
Implications:
- This approach offers a potential new surgical strategy for managing Meige syndrome.
- Minimizing postoperative deficits through predictive stimulation is crucial.
- Further research into bilateral pallidotomy for dystonia is warranted.
Keywords:
Deep brain stimulationDystoniaHigh frequency stimulationMeige syndromePallidotomyRadiofrequency lesions
