Related Experiment Video
Updated: Mar 3, 2026
02:22
Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection
Published on: April 12, 2024
1.1K
Recurrent Hyperammonemia After Abernethy Malformation Type 2 Closure: a Case Report.
1Department of gastroenterology, Shengjing Hospital Affiliated to China Medical University, Shenyang, Liaoning, China.
Annals of Hepatology
|April 21, 2017
Summary
Abernethy malformation, a rare congenital shunt, can cause encephalopathy. This case shows hyperammonemia recurrence after shunt closure, highlighting the need for established Abernethy malformation management strategies.
Area of Science:
- Hepatology
- Vascular Surgery
- Pediatric Gastroenterology
Background:
- Abernethy malformation is a rare congenital condition characterized by an extrahepatic portosystemic shunt.
- While often asymptomatic, 15% of patients develop clinical encephalopathy.
- Type 2 Abernethy malformation involves a complete diversion of portal blood directly into the systemic circulation.
Observation:
- A patient with type 2 Abernethy malformation presented with hyperammonemia and encephalopathy.
- Initial treatment involved successful shunt closure via interventional angiography.
- The patient experienced a recurrence of hyperammonemia three months post-procedure.
Findings:
- Diagnosis of Abernethy malformation is straightforward.
- The optimal management strategy for Abernethy malformation remains undetermined.
- This report details the first documented case of hyperammonemia recurrence following interventional shunt closure.
Implications:
- Recurrence of hyperammonemia post-intervention necessitates further investigation into long-term management.
- This case underscores the complexity of treating Abernethy malformation and its associated complications.
- Further research is crucial to establish effective therapeutic algorithms for Abernethy malformation patients.
Related Concept Videos
01:22Aneurysm IV: Nursing Management
552
Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
552
01:20Inborn Errors of Metabolism
963
Phenylketonuria (PKU) is a protein metabolism disorder characterized by high blood levels of the amino acid phenylalanine. This results from a mutation in the gene responsible for phenylalanine hydroxylase, an enzyme that converts phenylalanine into tyrosine. When this enzyme is deficient, phenylalanine builds up in the blood, leading to symptoms such as vomiting, rashes, seizures, growth deficiency, and severe mental retardation. An early diagnosis and a diet restricting phenylalanine intake...
963
01:23Urea Cycle
51.2K
The urea cycle describes how liver cells convert ammonia to urea. Ammonia is a toxic waste product of protein catabolism. Land animals must convert ammonia into the less toxic urea which can be safely eliminated by the kidneys through urine. Marine animals excrete ammonia directly, and the surrounding water dilutes the ammonia to safe levels.
51.2K
01:30Acute Respiratory Failure-III
1.0K
Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without...
1.0K
01:15Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
1.3K
Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
1.3K
01:28Esophageal Perforation-II: Clinical Manifestations and Management
859
Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
Clinical Manifestations:
859