Isolation and characterization of insulin-stimulated, high-affinity cAMP phosphodiesterases from rat liver

Phosphorylation of PDE4A5 by MAPKAPK2 attenuates fibrin degradation via p75 signalling.

Journal of biochemistry·2019

FBXW7 regulates DISC1 stability via the ubiquitin-proteosome system.

Molecular psychiatry·2017

Human phosphodiesterase 4D7 (PDE4D7) expression is increased in TMPRSS2-ERG-positive primary prostate cancer and independently adds to a reduced risk of post-surgical disease progression.

British journal of cancer·2015

The cAMP phosphodiesterase-4D7 (PDE4D7) is downregulated in androgen-independent prostate cancer cells and mediates proliferation by compartmentalising cAMP at the plasma membrane of VCaP prostate cancer cells.

British journal of cancer·2014

Epac and the high affinity rolipram binding conformer of PDE4 modulate neurite outgrowth and myelination using an in vitro spinal cord injury model.

British journal of pharmacology·2014

Disruption of the cyclic AMP phosphodiesterase-4 (PDE4)-HSP20 complex attenuates the β-agonist induced hypertrophic response in cardiac myocytes.

Journal of molecular and cellular cardiology·2011

Comparative methods for recombinant production and characterization of 1-deoxy-D-xylulose-5-phosphate synthase from bacterial and apicomplexan sources.

Methods in enzymology·2026

Current methods and applications in the study of 1-Deoxy-D-xylulose 5-phosphate synthase (DXPS).

Methods in enzymology·2026

Thiamine pyrophosphate-dependent enzymes in Toxoplasma gondii and functional significance of an apicoplast-localized pyruvate dehydrogenase.

Methods in enzymology·2026

Biochemical and cryo-EM studies of the pyruvate dehydrogenase complex from native cell extracts.

Methods in enzymology·2026

Synthesis of phosphonate and phosphinate analogs of 2-oxo acids for site-specific inhibition of thiamine-diphosphate-dependent dehydrogenases of 2-oxo acids in vivo.

Methods in enzymology·2026

Use of dihydroxyacetone synthase for the assimilation of methanol in E. coli.

Methods in enzymology·2026

Thermal compartments for efficient coupling of thermally incompatible enzymes into Cascade reactions via plasmonic photothermal conversion in hydrogels.

Journal of colloid and interface science·2026

Machine Learning-Guided Discovery of Natural BACE1 Inhibitors with Enzymatic and Cellular Validation.

ACS omega·2026

Coated bacterial enzymes: a one-step approach for enzymatic purification and immobilization.

Preparative biochemistry & biotechnology·2026

Bioconversion of macroalgae by enzymes from associated fungi into hydrolysates with cumulative antioxidant and antiglycemic properties for effective diabetes management.

Archives of microbiology·2026

Programmable Artificial Hydrolase Based on Minimalistic Cross-α/Cross-β Amyloid Assemblies.

ACS applied materials & interfaces·2026

Engineering of phosphoketolase from Bifidobacterium adolescentis for increased activity on non-phosphorylated substrates and application in a cell-free reaction system for ATP regeneration.

Methods in enzymology·2026

Related Experiment Videos

Isolation and characterization of insulin-stimulated, high-affinity cAMP phosphodiesterases from rat liver

Related Concept Videos

Phosphorylation of PDE4A5 by MAPKAPK2 attenuates fibrin degradation via p75 signalling.

FBXW7 regulates DISC1 stability via the ubiquitin-proteosome system.

Human phosphodiesterase 4D7 (PDE4D7) expression is increased in TMPRSS2-ERG-positive primary prostate cancer and independently adds to a reduced risk of post-surgical disease progression.

The cAMP phosphodiesterase-4D7 (PDE4D7) is downregulated in androgen-independent prostate cancer cells and mediates proliferation by compartmentalising cAMP at the plasma membrane of VCaP prostate cancer cells.

Epac and the high affinity rolipram binding conformer of PDE4 modulate neurite outgrowth and myelination using an in vitro spinal cord injury model.

Disruption of the cyclic AMP phosphodiesterase-4 (PDE4)-HSP20 complex attenuates the β-agonist induced hypertrophic response in cardiac myocytes.

Comparative methods for recombinant production and characterization of 1-deoxy-D-xylulose-5-phosphate synthase from bacterial and apicomplexan sources.

Current methods and applications in the study of 1-Deoxy-D-xylulose 5-phosphate synthase (DXPS).

Thiamine pyrophosphate-dependent enzymes in Toxoplasma gondii and functional significance of an apicoplast-localized pyruvate dehydrogenase.

Biochemical and cryo-EM studies of the pyruvate dehydrogenase complex from native cell extracts.

Synthesis of phosphonate and phosphinate analogs of 2-oxo acids for site-specific inhibition of thiamine-diphosphate-dependent dehydrogenases of 2-oxo acids in vivo.

Use of dihydroxyacetone synthase for the assimilation of methanol in E. coli.

Thermal compartments for efficient coupling of thermally incompatible enzymes into Cascade reactions via plasmonic photothermal conversion in hydrogels.

Machine Learning-Guided Discovery of Natural BACE1 Inhibitors with Enzymatic and Cellular Validation.

Coated bacterial enzymes: a one-step approach for enzymatic purification and immobilization.

Bioconversion of macroalgae by enzymes from associated fungi into hydrolysates with cumulative antioxidant and antiglycemic properties for effective diabetes management.

Programmable Artificial Hydrolase Based on Minimalistic Cross-α/Cross-β Amyloid Assemblies.

Engineering of phosphoketolase from Bifidobacterium adolescentis for increased activity on non-phosphorylated substrates and application in a cell-free reaction system for ATP regeneration.

Related Experiment Videos

Isolation and characterization of insulin-stimulated, high-affinity cAMP phosphodiesterases from rat liver

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