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Updated: Mar 3, 2026

Biochemical Measurement of Neonatal Hypoxia
Published on: August 24, 2011
Methemoglobinemia: Living with Dormant Devil
Dhiraj J Trivedi1, Bandi Joshiraj2, Vijay Bidkar3
1Department of Biochemistry, SDM College of Medical Sciences and Hospital, Dharwad, Karnataka India.
Abstract:
Methemoglobin is an oxidized form of hemoglobin. NADH methemoglobin reductase deficiency or inactivity is the cause of methemoglobin. Excessive production, resulting in accumulation, causes methemoglobinemia. It can be congenital or acquired. We present a case of dormant congenital methemoglobinemia detected accidentally on preoperative assessment, due to low oxygen saturation even at F1O2-1.0 associated with central cyanosis. The patient had 27.7 % methemoglobin, living his life without any complications. The patient was operated upon successfully for tympanoplasty and mastoidectomy under local anesthesia by taking proper precautions.
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