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Updated: Mar 3, 2026

Xenotransplantation of Human Stem Cells into the Chicken Embryo
Published on: July 11, 2010
Reassembling embryos in vitro from component stem cells
Caroline Kubaczka1,2,3, George Q Daley1,2,3
1Stem Cell Transplantation Program, Division of Pediatric Hematology and Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Boston, MA 02115, USA.
Abstract:
Researchers at the University of Cambridge, UK have succeeded in reconstructing mouse embryos by combining pluripotent embryonic and multipotent trophoblast stem cells in a 3D scaffold; the study from the laboratory of Professor Zernicka-Goetz, recently published in Science, provides a break-through tool to probe early mammalian development outside the uterus. Achieving a similar feat with human cells might necessitate reconsideration of the 14-day rule as a limitation of such research.
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