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Lysogenic Cycle of Bacteriophages00:43

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In contrast to the lytic cycle, phages infecting bacteria via the lysogenic cycle do not immediately kill their host cell. Instead, they combine their genome with the host genome, allowing the bacteria to replicate the phage DNA along with the bacterial genome. The incorporated copy of the phage genome is called the prophage. Some prophages can re-activate and enter the lytic cycle. This often occurs in response to a perturbation, such as DNA damage, but can also transpire in the absence of...
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Bacteriophages, or phages, are viruses that specifically infect bacteria, utilizing their genetic material to hijack host cellular machinery for replication. DNA bacteriophages employ single-stranded DNA (ssDNA) or double-stranded DNA (dsDNA) genomes. These phages exhibit diverse replication strategies and host interactions, influencing their ecological roles and applications in biotechnology and medicine.ssDNA BacteriophagesssDNA phages, with their small genomes, utilize unique strategies to...
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Bacteriophages, also known as phages, are specialized viruses that infect bacteria. A key characteristic of phages is their distinctive “head-tail” morphology. A phage begins the infection process (i.e., lytic cycle) by attaching to the outside of a bacterial cell. Attachment is accomplished via proteins in the phage tail that bind to specific receptor proteins on the outer surface of the bacterium. The tail injects the phage’s DNA genome into the bacterial cytoplasm. In the...
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Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins
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"French Phage Network"-Second Meeting Report.

Clara Torres-Barceló1, Oliver Kaltz2, Rémy Froissart3

  • 1Plant Populations and Bio-aggressors in Tropical Ecosystems (PVBMT) UMR, Pôle de Protection des Plantes, F-97410, Saint-Pierre, Reunion Island, France. clara.torres@univ-montp2.fr.

Viruses
|April 22, 2017
PubMed
Summary

French researchers created a network for bacteriophage (phage) studies, fostering collaboration across diverse approaches like structural biology and genetics. This network aims to advance phage applications in therapy and industry.

Keywords:
Francebacteriaco-evolutiongenomicsinfectionphagephage therapyresistancestructural biologyvirulence

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Area of Science:

  • Bacteriophage research encompasses structural biology, genetics, ecology, and evolution.
  • Focus on the diverse scientific disciplines involved in phage studies.

Background:

  • Bacteriophages (viruses of bacteria) have significant therapeutic and industrial potential.
  • Previous research highlights the broad applicability of phage biology.

Framework:

  • Establishment of the French Phage Network to connect researchers.
  • Facilitates exchange of complementary approaches and fosters new collaborations.

Implementation:

  • Summary of topics presented at the second French Phage Network meeting.
  • Meeting held in Marseille in November 2016.

Implications:

  • Advancing phage research through collaborative efforts.
  • Potential for enhanced therapeutic and industrial applications of bacteriophages.