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Related Experiment Videos

Mechanical ventilation in newborn infants.

J Kishan1, M E Valdez, N A Mir

  • 1Department of Paediatrics, Faculty of Medicine, Arab Medical University, Benghazi, Libya, SPLAJ.

African Journal of Medicine and Medical Sciences
|June 1, 1988
PubMed
Summary
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Mechanical ventilation (MV) in high-birth-weight neonates in a developing country showed a 43.9% survival rate. Complications included sepsis and pulmonary hemorrhage, with prematurity and late referrals being risk factors for poor outcomes.

Area of Science:

  • Neonatal Medicine
  • Pediatric Critical Care
  • Respiratory Physiology

Background:

  • Mechanical ventilation (MV) is a critical intervention for neonates with respiratory failure.
  • Data on MV outcomes in developing countries, particularly for infants weighing >= 1500g, are limited.
  • Understanding challenges and outcomes in resource-limited settings is crucial for improving neonatal care.

Purpose of the Study:

  • To describe the experience and outcomes of mechanical ventilation in newborn infants with birth weight >= 1500g in a developing country.
  • To identify indications, complications, and survival rates associated with MV in this population.
  • To determine risk factors for poor outcomes in neonates requiring MV.

Main Methods:

  • A retrospective review of 41 neonates (birth weight >= 1500g) treated with MV over 20 months.

Related Experiment Videos

  • Intermittent positive pressure ventilation and continuous positive airway pressure via nasotracheal intubation were employed.
  • Data collected included indications for MV, duration, complications, and survival rates.

    • Main Results:

    • The overall survival rate was 43.9%.
    • Common indications included respiratory distress syndrome (RDS), aspiration pneumonia, and apnea.
    • Frequent complications were sepsis (26.8%), pulmonary hemorrhage (21.9%), and congestive heart failure (17.1%). Post-extubation atelectasis occurred in 29.6%.

    Conclusions:

    • Mechanical ventilation in this cohort of higher-birth-weight neonates in a developing country was associated with significant morbidity and mortality.
    • Risk factors for poor outcomes included low birth weight (<2000g), prematurity, and delayed referral to the Neonatal Intensive Care Unit.
    • Improvements in neonatal care and timely interventions are needed to enhance survival rates.