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Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
Linear immunoglobulin A dermatosis: A case report
Fernando Valenzuela Ahumada1, Roberto Bustos Macaya2, Gabriela Paz Romero Morgado2
1Facultad de Medicina, Universidad de Chile, Santiago, Chile. Address: Departamento de Dermatología, Hospital Clínico Universidad de Chile, Santos Dumont 999, Independencia, Santiago, Chile .
Abstract:
We present the case of a sixty five year old woman with two months history of pruritus and hyperpigmented annular lesions on the trunk, buttocks and upper extremities. In addition, she presents vesicles with healthy skin on the basis, in the flexor aspect of wrists. No evidence of mucosal involvement. Histological study showed subepidermal vesicular dermatitis with inflammatory infiltrate of neutrophils and eosinophils. Direct immunofluorescence evidenced linear and continuous deposition of immunoglobulin A in basement membrane zone, compatible with linear immunoglobulin A disease.

