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Structure of a novel human granulocyte peptide with anti-ACTH activity
1Royal Victoria Hospital, Department of Medicine, Montreal, Quebec, Canada.
Biochemical and Biophysical Research Communications
|August 30, 1988
Abstract:
We report the purification, structure and biological properties of a peptide of novel sequence from human granulocytes that inhibits ACTH stimulated synthesis of corticosterone in rat adrenal cell suspensions. The peptide HP-4 is homologous to a previously described human granulocyte peptide HP-1 that has no anti-ACTH activity.