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Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms

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Published on: May 25, 2018

Genome edited animals: Learning from GM crops?

¹Science, Technology and Innovation Studies, The University of Edinburgh, Old Surgeons' Hall, High School Yards, Edinburgh, UK. ann.bruce@ed.ac.uk.

Transgenic Research

|April 23, 2017

Summary

Genome editing in livestock offers commercial potential but requires careful consideration of regulation, industry impact, and public acceptance. This study examines its integration into food systems, drawing lessons from genetically modified crops.

Keywords:

Genome edited livestock Industry structure Production systems Regulation Veterinarians

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Area of Science:

Agricultural Science
Biotechnology
Food Systems Analysis

Background:

Genome editing in livestock is advancing towards commercialization, raising regulatory and public acceptance concerns.
Lessons from the commercialization of genetically modified (GM) crops are being applied to livestock genome editing.
A systemic approach is needed to understand the complexities of integrating genome-edited animals into food production.

Purpose of the Study:

To explore the complexities and ambiguities of incorporating genome-edited animals into food production systems.
To examine current applications of genome editing in livestock from a historical technological perspective.
To analyze the implications of regulation on different livestock production sectors, particularly the veterinary sector.

Main Methods:

Review of current genome editing applications in livestock.
Analysis of historical technological applications in agriculture.
Examination of regulatory frameworks, with a focus on the EU.
Systemic analysis of food production and veterinary sectors.

Main Results:

Genome editing in livestock presents both opportunities and challenges for commercialization.
The regulatory landscape for genome-edited animals requires careful consideration, potentially differing from GM crop regulations.
Public perception and acceptance are critical factors for successful integration.

Conclusions:

Genome editing in livestock necessitates a comprehensive regulatory approach, informed by past experiences with GM crops.
Engaging a wider range of food system actors beyond science and regulation is crucial for responsible development.
Further research is needed to address the multifaceted implications of genome-edited animals in food production.