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Updated: Mar 3, 2026

Ex Vivo Organotypic Corneal Model of Acute Epithelial Herpes Simplex Virus Type I Infection
Published on: November 3, 2012
Herpes zoster keratitis development after acute retinal necrosis
Waseem H Ansari1, Francesco Pichi2, Paula E Pecen3
1Cleveland Clinic Foundation, Cole Eye Institute, 9500 Euclid Avenue Mail Code i13, Cleveland, OH, 44195, USA. Ansariw@ccf.org.
Purpose:
To report a case of herpes zoster keratitis in a patient undergoing treatment for herpetic acute retinal necrosis.
Methods:
Case report.
Results:
A 71 year old male presented with acute retinal necrosis of the left eye due to herpes zoster and was treated with intravitreal foscarnet and oral valcyclovir. He developed a retinal detachment and underwent surgical repair. After four weeks, he developed an ipsilateral herpetic zoster keratitis demonstrated by Rose-Bengal staining that was responsive to topical ganciclovir gel.
Conclusions:
This case report describes the unusual development of herpes zoster keratitis after the development of unilateral acute retinal necrosis (ARN) in a patient on antiviral treatment.

