Ivermectin to reduce malaria transmission II. Considerations regarding clinical development pathway

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Carlos Chaccour1,2,3, N Regina Rabinovich4,5

  • 1ISGlobal, Barcelona Ctr. Int. Health Res. (CRESIB), Hospital Clínic, Universitat de Barcelona, Barcelona, Spain. carlos.chaccour@isglobal.org.

Malaria Journal
|April 25, 2017
PubMed

The development of ivermectin as a complementary vector control tool will require good quality evidence. This paper reviews the different eco-epidemiological contexts in which mass drug administration with ivermectin could be useful. Potential scenarios and pharmacological strategies are compared in order to help guide trial design. The rationale for a particular timing of an ivermectin-based tool and some potentially useful outcome measures are suggested.

Keywords:
AnophelesClinical developmentClinical trialsEndectocideIvermectin

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