Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Brain Imaging01:14

Brain Imaging

805
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
805

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Responsive stimulation of the thalamus for idiopathic generalized epilepsy: Results of the randomized controlled NAUTILUS trial through 18 months.

Epilepsia·2026
Same author

Direct electrical stimulation of the human amygdala enhances recognition memory for objects but not scenes.

Communications biology·2026
Same author

Independent contributions of language activations in left and right temporal cortex to aphasia outcomes after stroke.

Imaging neuroscience (Cambridge, Mass.)·2026
Same author

Postapproval Study for Brain-Responsive Neurostimulation for Drug-Resistant Focal Epilepsy: Three-Year Efficacy and Interim Safety Results.

Neurology·2026
Same author

Increasing capacity for epilepsy self-management via a hub and spoke implementation model: Clinician perspectives from epilepsy centers in the United States.

Epilepsy & behavior : E&B·2026
Same author

A wireless, 60-channel, AI-enabled neurostimulation platform.

Brain stimulation·2025
Same journal

Pitch selectivity in ferret auditory cortex.

Current biology : CB·2026
Same journal

A cell size-dependent competition between geometry and polarity governs nuclear and spindle positioning in early embryos.

Current biology : CB·2026
Same journal

Trophic cascades drive sustainability in the agricultural heritage rice-fish coculture system.

Current biology : CB·2026
Same journal

Tracking Satb2-positive retinal ganglion cells in zebrafish unveils developmental functional reorganization.

Current biology : CB·2026
Same journal

RhoGAP54D promotes cell size asymmetry and inhibits pulsatile myosin activity in Drosophila neural stem cells.

Current biology : CB·2026
Same journal

Increased rates of hybridization in swordtails are associated with water pollution.

Current biology : CB·2026
See all related articles

Related Experiment Video

Updated: Mar 3, 2026

Transcranial Direct Current Stimulation tDCS for Memory Enhancement
10:37

Transcranial Direct Current Stimulation tDCS for Memory Enhancement

Published on: September 18, 2021

16.0K

Direct Brain Stimulation Modulates Encoding States and Memory Performance in Humans.

Youssef Ezzyat1, James E Kragel1, John F Burke2

  • 1Department of Psychology, University of Pennsylvania, Philadelphia, PA 19104, USA.

Current Biology : CB
|April 25, 2017
PubMed
Summary
This summary is machine-generated.

Targeted electrical stimulation can improve memory recall by enhancing neural encoding states. This brain stimulation technique shows promise for treating memory dysfunction by optimizing memory encoding efficiency.

Keywords:
deep brain stimulationepilepsyepisodic memoryfree recallintracranial EEGlocal field potentialmultivariate classification

More Related Videos

Modulating Cognition Using Transcranial Direct Current Stimulation of the Cerebellum
11:47

Modulating Cognition Using Transcranial Direct Current Stimulation of the Cerebellum

Published on: February 15, 2015

30.3K
Transcranial Direct Current Stimulation and Simultaneous Functional Magnetic Resonance Imaging
13:35

Transcranial Direct Current Stimulation and Simultaneous Functional Magnetic Resonance Imaging

Published on: April 27, 2014

22.6K

Related Experiment Videos

Last Updated: Mar 3, 2026

Transcranial Direct Current Stimulation tDCS for Memory Enhancement
10:37

Transcranial Direct Current Stimulation tDCS for Memory Enhancement

Published on: September 18, 2021

16.0K
Modulating Cognition Using Transcranial Direct Current Stimulation of the Cerebellum
11:47

Modulating Cognition Using Transcranial Direct Current Stimulation of the Cerebellum

Published on: February 15, 2015

30.3K
Transcranial Direct Current Stimulation and Simultaneous Functional Magnetic Resonance Imaging
13:35

Transcranial Direct Current Stimulation and Simultaneous Functional Magnetic Resonance Imaging

Published on: April 27, 2014

22.6K

Area of Science:

  • Neuroscience
  • Cognitive Science
  • Neuromodulation

Background:

  • Memory failure is often linked to ineffective information encoding in the brain.
  • Understanding neural encoding states is crucial for improving memory.
  • Electrical stimulation presents a potential method for modulating brain activity and memory.

Purpose of the Study:

  • To investigate if targeted electrical stimulation can modulate neural encoding states.
  • To determine the impact of such stimulation on subsequent memory outcomes.
  • To identify specific conditions under which stimulation effectively enhances or impairs memory.

Main Methods:

  • Utilized intracranial electroencephalography (EEG) recordings from neurosurgical epilepsy patients.
  • Trained multivariate classifiers to distinguish neural activity patterns predicting memory success versus failure.
  • Applied targeted electrical stimulation during memory learning tasks based on real-time classifier output.

Main Results:

  • Electrical stimulation modulated neural encoding-state estimates and memory recall.
  • Stimulation enhanced memory when applied during periods of low encoding efficiency.
  • Conversely, stimulation impaired memory when applied during high encoding efficiency, indicating a context-dependent effect.

Conclusions:

  • The findings demonstrate that the timing of electrical stimulation is critical for modulating memory.
  • Stimulation's effects on memory are linked to its ability to influence neural activity associated with memory encoding.
  • This research provides a foundation for developing targeted neuromodulation strategies for memory dysfunction.