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Exercise-modulated epigenetic markers and inflammatory response in COPD individuals: A pilot study

Ivy Reichert Vital da Silva1, Cintia Laura Pereira de Araujo2, Gilson Pires Dorneles3

  • 1Programa de Pós Graduação em Biociências e Reabilitação do Centro Universitário Metodista-IPA, Porto Alegre, RS, Brazil.

Respiratory Physiology & Neurobiology
|April 25, 2017
PubMed
Summary

Exercise impacts epigenetic signals in chronic obstructive pulmonary disease (COPD). Pulmonary rehabilitation with exercise significantly altered DNA methylation and reduced inflammatory markers like interleukin-6 (IL-6) and interleukin-8 (IL-8) in COPD patients.

Keywords:
COPDExerciseGlobal DNA methylationGlobal histone H4 acetylationInflammatory response

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