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Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
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Head and neck lymphomas - a retrospective ten-year observation
Marcelina Niemiec1, Grażyna Stryjewska-Makuch1, Małgorzata Janik2
1Department of Laryngology and Laryngological Oncology, Silesian Medical University in Katowice, Poland.
Contemporary Oncology (Poznan, Poland)
|April 25, 2017
Summary
Head and neck lymphomas show an increasing incidence, particularly non-Hodgkin
Area of Science:
- Oncology
- Hematology
- Head and Neck Surgery
Background:
- Lymphomas are cancers of the lymphatic system with a noted rise in incidence.
- Head and neck lymphomas represent a significant clinical challenge.
Purpose of the Study:
- To investigate the incidence trends of head and neck lymphomas.
- To analyze the characteristics of these tumors in the head and neck region.
Main Methods:
- Retrospective analysis of 58 lymphoma cases from 2005-2014.
- Evaluation of lymphoma location, histology, patient demographics, and risk factors.
Main Results:
- Non-Hodgkin's lymphomas (NHL) comprised 67.53%, with diffuse large B-cell lymphoma (DLBCL) being most common (51.92%).
- Primary lesions were most frequent in lymph nodes; extranodal sites included Waldeyer ring (54.54%) and palatine tonsil (40.90%).
- A significant upward trend in lymphoma incidence, especially NHL, was observed.
Conclusions:
- Head and neck lymphomas are increasing, predominantly NHL.
- Understanding the specific characteristics and trends is crucial for early diagnosis and treatment of head and neck cancers.
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