Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Opioid Analgesics: Synthetic and Semisynthetic Opioids01:15

Opioid Analgesics: Synthetic and Semisynthetic Opioids

1.3K
Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
1.3K
Opioid Analgesics: Morphine and Other Natural Cogeners01:20

Opioid Analgesics: Morphine and Other Natural Cogeners

1.2K
Opioids are a class of drugs that mimic endogenous opioid peptides and act on opioid receptors, and help in pain relief. These compounds are classified as natural, synthetic, or semi-synthetic. Natural opioids, like morphine, codeine, and thebaine, are derived from the opium poppy plant (Papaver somniferum or Papaver album) and are termed opiates. Synthetic opioids are artificial, while semi-synthetic opioids combine natural and synthetic compounds. Morphine, a prototypical opioid, possesses a...
1.2K
Analgesia and Pain Management01:25

Analgesia and Pain Management

2.4K
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
2.4K
Opioid Receptors: Overview01:22

Opioid Receptors: Overview

5.4K
Opioid receptors, including the mu (μ, MOR), delta (δ, DOR), and kappa (κ, KOR) types, belong to the rhodopsin family of G protein-coupled receptors. These receptors are located throughout the central and peripheral nervous systems and in non-neuronal tissues such as macrophages and astrocytes. Opioid receptor ligands can be categorized into agonists or antagonists. Highly selective agonists include [d-Ala2, MePhe4, Gly(ol)5]-enkephalin or DAMGO for MOR, [D-Pen2,...
5.4K
Drug Classes and Categories01:25

Drug Classes and Categories

3.3K
Drugs can be classified according to their chemical composition or their intended therapeutic application. For instance, anti-infective agents that possess the ability to eliminate pathogens or suppress their growth and reproduction can be grouped based on the organisms they target or their chemical structure. Furthermore, drugs can be divided into prescription, nonprescription, or controlled substances. Prescription medications, such as antibiotics, require oversight from a licensed healthcare...
3.3K
Drugs Affecting GI Tract Motility: Opioids as Antidiarrheal Agents01:17

Drugs Affecting GI Tract Motility: Opioids as Antidiarrheal Agents

775
Diarrhea, a condition marked by frequent loose or watery bowel movements, can be triggered by multiple factors such as viral or bacterial infections, food intolerances, anxiety, medications, and digestive disorders. Symptoms may include abdominal pain, bloating, nausea, and cramping. Severe or prolonged diarrhea can lead to complications like electrolyte imbalances, malnutrition, and dehydration if left untreated.
Opioids, widely used antidiarrheal agents, mitigate diarrhea by slowing down...
775

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hydrolysis and depletion of phosphatidylglycerol at peak murine acute lung injury.

Journal of lipid research·2026
Same author

Blistering Bulbs: The Hidden Dangers of Garlic as a Home Remedy.

Cureus·2026
Same author

Measuring burnout and professional fulfillment among emergency medicine residency program leaders in the United States: a cross-sectional survey study.

Clinical and experimental emergency medicine·2024
Same author

Trends and predictors of unfilled emergency medicine residency positions: A comparative analysis of the 2023 and 2024 Match cycles.

AEM education and training·2024
Same author

Paxlovid-Induced Tacrolimus Toxicity in the Treatment of COVID-19: A Case Report.

Cureus·2023
Same author

Where Have All the FLOWERS Gone? A Multicenter Investigation of Frequent Users of Midwest Emergency Department Services During the COVID-19 Stay-at-home Orders.

The western journal of emergency medicine·2022

Related Experiment Video

Updated: Mar 3, 2026

Author Spotlight: An Efficient Methodology to Confidently Differentiate and Characterize Fentanyl Analogs
10:13

Author Spotlight: An Efficient Methodology to Confidently Differentiate and Characterize Fentanyl Analogs

Published on: November 8, 2024

2.9K

State Emergency Department Opioid Guidelines: Current Status.

Robert I Broida1, Tanner Gronowski2, Andrew F Kalnow2

  • 1US Acute Care Solutions, Risk Management Department, Canton, Ohio.

The Western Journal of Emergency Medicine
|April 25, 2017
PubMed
Summary

Seventeen states have established opioid prescribing guidelines for emergency medicine, focusing on limiting prescriptions and preventing abuse. This research categorizes these guidelines to inform future state-level efforts in opioid stewardship.

More Related Videos

Evaluation of Capnography Sampling Line Compatibility and Accuracy when Used with a Portable Capnography Monitor
07:51

Evaluation of Capnography Sampling Line Compatibility and Accuracy when Used with a Portable Capnography Monitor

Published on: September 29, 2020

9.7K
Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation
16:02

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation

Published on: February 10, 2023

3.4K

Related Experiment Videos

Last Updated: Mar 3, 2026

Author Spotlight: An Efficient Methodology to Confidently Differentiate and Characterize Fentanyl Analogs
10:13

Author Spotlight: An Efficient Methodology to Confidently Differentiate and Characterize Fentanyl Analogs

Published on: November 8, 2024

2.9K
Evaluation of Capnography Sampling Line Compatibility and Accuracy when Used with a Portable Capnography Monitor
07:51

Evaluation of Capnography Sampling Line Compatibility and Accuracy when Used with a Portable Capnography Monitor

Published on: September 29, 2020

9.7K
Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation
16:02

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation

Published on: February 10, 2023

3.4K

Area of Science:

  • Public Health
  • Emergency Medicine
  • Pharmacology

Background:

  • Opioid prescribing in emergency medicine is a significant public health concern.
  • Variability exists in state-level regulations for opioid prescribing.

Purpose of the Study:

  • To evaluate and categorize current state-sponsored opioid guidelines specific to emergency medicine (EM) practice.
  • To identify states with existing EM opioid prescribing guidelines.

Main Methods:

  • A comprehensive search of state-specific opioid prescribing guidelines and policies for emergency departments was conducted.
  • An online query and follow-up email requests to state chapters of the American College of Emergency Physicians (ACEP) were utilized.

Main Results:

  • Seventeen states were identified as having emergency department-specific opioid prescribing guidelines.
  • Guidelines were categorized into four main areas: limiting opioid prescriptions (67 recommendations), preventing abuse/diversion (56 recommendations), addiction-related issues (29 recommendations), and community resources (24 recommendations).
  • Current state guidelines primarily focus on limiting opioid prescriptions and screening patients for potential abuse or diversion.

Conclusions:

  • This study identifies and categorizes the opioid prescribing guideline efforts in 17 states.
  • The findings provide a foundation for other states to develop or enhance their own opioid stewardship initiatives.