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Updated: Mar 3, 2026

Monitoring Kinase and Phosphatase Activities Through the Cell Cycle by Ratiometric FRET
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Playing polo during mitosis: PLK1 takes the lead

G Combes1,2, I Alharbi1,2, L G Braga1,2

  • 1Program in Molecular and Cellular biology, Faculty of Medicine, Université Laval, Quebec City, Quebec, Canada.

Oncogene
|April 25, 2017
PubMed
Summary

Polo-like kinase 1 (PLK1) masterfully regulates key mitotic kinases, including Aurora B, Haspin, MPS1, BUB1, and BUBR1, ensuring accurate cell division. This review highlights PLK1's crucial role in controlling these kinases for mitotic fidelity.

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