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Published on: June 2, 2015
Behcet Disease Initially Presenting as Deep Venous Thrombosis: A Case Report
Arun Gurunathan1, David T Teachey, Kudakwashe R Chikwava
1*Division of Oncology Departments of †Pediatrics §Pathology and Laboratory Medicine ¶Division of Hematology, The Children's Hospital of Philadelphia Departments of ‡Pediatrics ∥Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
Behcet disease, a vasculitis, can initially present as deep vein thrombosis in children. Early screening for rheumatologic conditions is crucial for diagnosing Behcet disease in pediatric patients with unprovoked thrombosis.
Area of Science:
- Rheumatology
- Pediatric Vasculitis
Background:
- Behcet disease is a multisystemic vasculitis.
- It has a tendency for thrombosis.
- Key features like mucocutaneous ulcers, arthritis, and uveitis may not be immediately apparent.
Observation:
- An 8-year-old patient presented with spontaneous bilateral deep lower extremity venous thromboses.
- This presentation prompted a rheumatologic screening.
Findings:
- The patient was diagnosed with Behcet disease.
- Deep venous thromboses served as the initial clinical manifestation.
Implications:
- Deep vein thrombosis can be the first sign of Behcet disease in pediatric cases.
- Screening for rheumatologic diseases is vital in children with unexplained thrombosis.
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