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Breast-Feeding Analgesia in Infants: An Update on the Current State of Evidence
Britney Benoit1, Ruth Martin-Misener, Margot Latimer
1School of Nursing (Ms Benoit and Drs Martin-Misener, Latimer, and Campbell-Yeo) and Departments of Psychology & Neuroscience (Dr Campbell-Yeo) and Pain, Anesthesia and Perioperative Medicine, Faculty of Medicine (Dr Latimer), Dalhousie University, Halifax, Nova Scotia, Canada; and Centre for Pediatric Pain Research (Ms Benoit and Drs Latimer and Campbell-Yeo), Maternal Newborn Program (Ms Benoit), and Department of Pediatrics (Dr Campbell-Yeo), IWK Health Centre, Halifax, Nova Scotia, Canada.
Insights
Direct breast-feeding effectively reduces procedural pain in full-term infants, outperforming other methods. However, expressed breast milk alone is not consistently effective for pain management in either full-term or preterm infants.
Area of Science:
- Neonatal care
- Pain management
- Lactation science
Background:
- Procedural pain is a significant concern in neonates.
- Non-pharmacological interventions are sought to manage infant pain.
- Breast milk offers potential benefits, but evidence requires synthesis.
Purpose of the Study:
- To synthesize evidence on breast-feeding and expressed breast milk for procedural pain reduction in infants.
- To compare the efficacy of direct breast-feeding versus expressed breast milk.
- To evaluate effectiveness in both full-term and preterm infants.
Main Methods:
- Systematic literature search of PubMed, CINAHL, and EMBASE.
- Inclusion of 21 studies (15 on full-term, 6 on preterm infants).
- Assessment of interventions including direct breast-feeding, expressed breast milk, and controls.
Main Results:
- Direct breast-feeding was superior to maternal holding, topical anesthetics, and music therapy in full-term infants.
- Direct breast-feeding was as or more effective than sweet solutions for full-term infants.
- Expressed breast milk showed inconsistent pain reduction in both full-term and preterm infants.
- Studies often had moderate to high risk of bias.
Conclusions:
- Sufficient evidence supports direct breast-feeding for procedural pain management in full-term infants.
- Expressed breast milk alone is not currently recommended as an adequate intervention for procedural pain.
- Further high-quality research may be needed, particularly for preterm infants.
Abstract:
To provide an updated synthesis of the current state of the evidence for the effectiveness of breast-feeding and expressed breast milk feeding in reducing procedural pain in preterm and full-term born infants. A systematic search of key electronic databases (PubMed, CINAHL, EMBASE) was completed. Of the 1032 abstracts screened, 21 were found eligible for inclusion. Fifteen studies reported on the use of breast-feeding or expressed breast milk in full-term infants and 6 reported on preterm infants. Direct breast-feeding was more effective than maternal holding, maternal skin-to-skin contact, topical anesthetics, and music therapy, and was as or more effective than sweet tasting solutions in full-term infants. Expressed breast milk was not consistently found to reduce pain response in full-term or preterm infants. Studies generally had moderate to high risk of bias. There is sufficient evidence to recommend direct breast-feeding for procedural pain management in full-term infants. Based on current evidence, expressed breast milk alone should not be considered an adequate intervention.
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