Related Experiment Videos
Release of a virus coded glycoprotein from herpes simplex virus type 1 infected cells
K H Tiedemann1, H Hampl, K O Habermehl
1Institut für Klinische und Experimentelle Virologie, Freien Universität Berlin, Germany.
Molecular Biology Reports
|January 1, 1988
Abstract:
HEp-2 cells, which were infected with HSV-1, excrete besides other proteins a soluble glycoprotein (Mr 125,000-130,000) related to the virus protein gC. The excretion of the glycoprotein and the production of extracellular virus particles is reduced to a similar extent when the cells were treated with monensin. Possible consequences of the excretion of soluble viral proteins to a modulation of the immune response are discussed.