Common Medical Comorbidities Correlated With Poor Outcomes in Hip Periprosthetic Infection

Periprosthetic infection has been linked to risk factors such as diabetes, obesity, and smoking among others. This study examined the relationship between common patient comorbidities and hip periprosthetic infection outcomes.

We retrospectively reviewed the records of 149 culture-positive periprosthetic hip infections at our tertiary care center that underwent treatment between 2005 and 2015. Baseline characteristics and common comorbidities were analyzed with relation to rates of successfully treated infection, total surgeries for infection, and cumulative length of hospitalization using multivariate analysis.

Patients with coronary artery disease or anemia had significantly lower rate of successfully treated infection. Patients with anemia or chronic pulmonary disease underwent significantly more surgery, and patients with chronic pulmonary disease, psychiatric disease, anemia, or diabetes spent significantly longer time in hospital.

Potentially modifiable cardiovascular, respiratory, and psychiatric diseases were associated with a decreased rate of successfully treated infection, more surgery, and longer hospitalization in treatment for hip periprosthetic infection in multivariate analysis.