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Updated: Mar 3, 2026

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids
Published on: December 23, 2022
A tenebrous tale: malignant melanoma of the oesophagus
Jane O'Sullivan1, Justin Matthias Hintze1,2, Peter Molony3
1Department of Surgery, Tallaght Hospital, Tallaght D24, Ireland.
Abstract:
A 57-year-old man presented with a 4-month history of worsening symptoms of oesophageal obstruction. The physical examination was unremarkable. An oesophagogastroduodenoscopy revealed an exophytic tumour in the distal oesophagus. A biopsy demonstrated malignant melanoma. Staging of the melanoma showed disseminated lymph node and bony-spine metastases. He had no prior history of cutaneous or ocular melanoma. Following full multidisciplinary team input, he was palliated with a metal mesh stent and immunotherapy. He died 3 months later following community management.
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