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Related Concept Videos

Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

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Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
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The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
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Pleural Effusion Overview
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Appendicitis-I: Introduction01:22

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The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
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Related Experiment Video

Updated: Mar 3, 2026

Evaluating Therapeutic Interventions in the SHIP-deficient Mouse Model of Crohn Disease-like Ileitis and Fibrosis
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Whipple's Disease Manifested as Recurrent Ascites.

Ali Aamar1, Kamraan Madhani1, Muhammad S Anwar1

  • 1Internal Medicine, Yale Waterbury.

Cureus
|April 26, 2017
PubMed
Summary

This case report highlights a rare presentation of Whipple's disease. Ascites, often linked to liver issues, was successfully treated with antibiotics, revealing a less common cause.

Keywords:
ascitessmall intestinewhipple’s disease

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Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Internal Medicine

Background:

  • Whipple's disease is a rare systemic infection typically causing chronic diarrhea and abdominal pain.
  • Ascites, or fluid accumulation in the abdomen, is an uncommon manifestation of Whipple's disease.

Observation:

  • A 47-year-old male presented with a three-month history of diarrhea and abdominal distention.
  • Physical examination revealed ascites, with laboratory results suggesting it was not due to portal hypertension.

Findings:

  • Enteroscopy identified erythematous changes in the duodenum and jejunum.
  • Biopsies confirmed the presence of periodic acid-Schiff (PAS) positive macrophages, indicative of Whipple's disease.

Implications:

  • This case underscores the importance of considering Whipple's disease in patients with unexplained ascites, even without typical gastrointestinal symptoms.
  • Prompt diagnosis and treatment with antibiotics, such as intravenous ceftriaxone, can lead to significant clinical improvement.