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Updated: Mar 3, 2026

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus
Published on: June 10, 2025
[Diagnostic approach of erythroderma in the adult]
César Alfonso Maldonado-García1, Ana Paula Orozco-Anahuati
1Centro Dermatológico "Dr. Ladislao de la Pascua", Secretaría de Salud de la Ciudad de México, Ciudad de México, México. docmaldonado1@hotmail.com.
Abstract:
Erythroderma consists on erythema and scaling that covers more than 90% of the cutaneous surface. It has multiple causes and for the most common we can use the acronym PALM (psoriasis, atopic dermatitis, lymphoproliferative disease and medication). It is important to diagnose the cause in order to get a prognosis and a targeted treatment. In 30% of the cases the cause is not evident and the patient requires periodic assessment to rule out evolution to a lymphoproliferative disease. In many cases, erythroderma is a chronic disease but it can also be a life-threatening dermatologic urgency that requires hospitalization.
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