Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Surface plasmon coupling electrochemiluminescence assay based on the use of AuNP@C<sub>3</sub>N<sub>4</sub>QD@mSiO<sub>2</sub> for the determination of the Shiga toxin-producing Escherichia coli (STEC) gene.

Mikrochimica acta·2019
Same author

Ultrasensitive Detection of Capsaicin in Oil for Fast Identification of Illegal Cooking Oil by SERRS.

ACS omega·2019
Same author

A central role for MeCP2 in the epigenetic repression of miR-200c during epithelial-to-mesenchymal transition of glioma.

Journal of experimental & clinical cancer research : CR·2019
Same author

Development of the triazole-fused pyrimidine derivatives as highly potent and reversible inhibitors of histone lysine specific demethylase 1 (LSD1/KDM1A).

Acta pharmaceutica Sinica. B·2019
Same author

Corrigendum to "Synthesis and preliminary antiproliferative activity of new pteridin-7(8H)-one derivatives" [Eur. J. Med. Chem. 143 (2018) 1396-1405].

European journal of medicinal chemistry·2019
Same author

Gene manipulation in liver ductal organoids by optimized recombinant adeno-associated virus vectors.

The Journal of biological chemistry·2019

Related Experiment Video

Updated: Mar 3, 2026

A Filter-based Surface Enhanced Raman Spectroscopic Assay for Rapid Detection of Chemical Contaminants
08:13

A Filter-based Surface Enhanced Raman Spectroscopic Assay for Rapid Detection of Chemical Contaminants

Published on: February 19, 2016

9.9K

Surface-Enhanced Raman Scattering (SERS) Active Gold Nanoparticles Decorated on a Porous Polymer Filter.

Lei Chen1,2, Huiying Yan1, Xiangxin Xue1

  • 11 Key Laboratory of Preparation and Applications of Environmental Friendly Materials, Ministry of Education; Department of Chemistry, Jilin Normal University, Siping, China.

Applied Spectroscopy
|April 26, 2017
PubMed
Summary

Researchers developed a novel method to attach gold nanoparticles to a 3D polymer surface for sensitive trace detection using surface-enhanced Raman scattering (SERS). This creates a highly effective SERS-active substrate for real-time analysis.

Keywords:
3D nanoporous polymerSERSSurface-enhanced Raman scatteringbiomolecule detectionenvironmental monitoringgold-nanoparticle-decorated polymer filterin situ SERS

More Related Videos

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging
06:19

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging

Published on: June 9, 2023

2.1K
Optical Trapping of Plasmonic Nanoparticles for In Situ Surface-Enhanced Raman Spectroscopy Characterizations
06:19

Optical Trapping of Plasmonic Nanoparticles for In Situ Surface-Enhanced Raman Spectroscopy Characterizations

Published on: June 23, 2022

3.0K

Related Experiment Videos

Last Updated: Mar 3, 2026

A Filter-based Surface Enhanced Raman Spectroscopic Assay for Rapid Detection of Chemical Contaminants
08:13

A Filter-based Surface Enhanced Raman Spectroscopic Assay for Rapid Detection of Chemical Contaminants

Published on: February 19, 2016

9.9K
Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging
06:19

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging

Published on: June 9, 2023

2.1K
Optical Trapping of Plasmonic Nanoparticles for In Situ Surface-Enhanced Raman Spectroscopy Characterizations
06:19

Optical Trapping of Plasmonic Nanoparticles for In Situ Surface-Enhanced Raman Spectroscopy Characterizations

Published on: June 23, 2022

3.0K

Area of Science:

  • Materials Science: Development of novel SERS-active substrates.
  • Nanotechnology: Assembly of gold nanoparticles on polymer surfaces.
  • Analytical Chemistry: Application of SERS for trace detection.

Background:

  • Surface-enhanced Raman scattering (SERS) requires specialized substrates for sensitive molecular detection.
  • Existing SERS substrates often lack tunability and in situ monitoring capabilities.
  • Polymer films offer a versatile platform for substrate fabrication.

Purpose of the Study:

  • To design and fabricate a tunable SERS-active substrate using gold nanoparticles on a 3D polymer film.
  • To demonstrate the in situ monitoring capability of the developed substrate using Raman spectroscopy.
  • To evaluate the substrate's sensitivity and homogeneity for trace molecule detection.

Main Methods:

  • Fabrication of a SERS-active substrate by assembling gold nanoparticles onto a polyhexamethylene adipamide (Nylon66) polymer film template.
  • Utilized 4-mercaptobenzoic acid as a probe molecule to assess scattering efficiency and signal homogeneity.
  • Demonstrated detection of a biotin-avidin complex using the gold-nanoparticle-decorated polymer film.

Main Results:

  • Successfully created a 'hotspot'-rich gold-nanoparticle-decorated polymer substrate.
  • The substrate exhibited high sensitivity for trace detection of target molecules.
  • Demonstrated the feasibility of in situ SERS measurements on the fabricated substrate.

Conclusions:

  • The developed 3D nanoporous polymer substrate decorated with gold nanoparticles is a highly sensitive and tunable SERS-active material.
  • The in situ SERS capability offers a powerful advantage for real-time microanalytical applications.
  • This technology holds significant potential for environmental monitoring and biomolecule detection.