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Updated: Mar 3, 2026
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In Vivo Imaging and Tracking of Technetium-99m Labeled Bone Marrow Mesenchymal Stem Cells in Equine Tendinopathy
Published on: December 9, 2015
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Skeletal Scintigraphy
Jaime L Montilla-Soler1, Rikesh Makanji
1Department of Radiology, Moffitt Cancer Center, Tampa, FL. Jaime.MontillaSoler@Moffitt.org.
Cancer Control : Journal of the Moffitt Cancer Center
|April 26, 2017
Summary
Skeletal scintigraphy is crucial for evaluating bone cancers and metastases. Advances in radiopharmaceuticals and imaging techniques significantly improve the detection and management of skeletal metastatic disease.
Area of Science:
- Nuclear medicine
- Oncology
- Radiology
Background:
- Skeletal scintigraphy is a key diagnostic tool for primary and metastatic bone neoplasms.
- It aids in the initial and ongoing assessment of the skeletal system in cancer patients.
Purpose of the Study:
- To review radiopharmaceuticals, nuclear medicine imaging, and oncological applications for skeletal metastases in adults.
- To discuss the advantages and limitations of current and future technologies for evaluating skeletal metastatic disease.
Main Methods:
- Literature review of pertinent studies on skeletal scintigraphy and metastatic disease.
- Discussion of nuclear medicine and positron emission tomography techniques for skeletal evaluation.
Main Results:
- Skeletal scintigraphy effectively identifies osteoblastic bone metastases.
- Advancements in radiopharmaceuticals (e.g., fludeoxyglucose F 18, sodium fluoride F 18) and imaging (e.g., PET/CT, PET/MRI) enhance detection accuracy.
Conclusions:
- Skeletal scintigraphy plays a vital role in cancer diagnosis, staging, and treatment monitoring for skeletal diseases.
- Combined diagnostic and therapeutic nuclear agents show promise for treating bone metastases, particularly in prostate cancer, with potential for broader application.
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