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Using Micro-computed Tomography for the Assessment of Tumor Development and Follow-up of Response to Treatment in a Mouse Model of Lung Cancer

Using Micro-computed Tomography for the Assessment of Tumor Development and Follow-up of Response to Treatment in a Mouse Model of Lung Cancer

Published on: May 20, 2016

X-ray micro computed-tomography.

Emily Baird¹, Gavin Taylor¹

¹Department of Biology, Lund University, Lund 223 62, Sweden.

Current Biology : CB

|April 26, 2017

Summary

This summary is machine-generated.

Create 3D models of biological samples using advanced X-ray micro-computed tomography. This technique provides detailed insights into sample structures for research and analysis.

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Area of Science:

* Biological imaging
* Materials science
* Biomedical engineering

Background:

* Traditional methods for biological sample analysis can be destructive or offer limited structural detail.
* X-ray micro-computed tomography (micro-CT) offers a non-destructive approach to visualize internal structures.

Purpose of the Study:

* To describe a methodology for generating high-resolution three-dimensional (3D) models of biological samples.
* To demonstrate the application of X-ray micro-computed tomography (micro-CT) for biological research.

Main Methods:

* Utilizing X-ray micro-computed tomography (micro-CT) to scan biological specimens.
* Employing specialized software for image reconstruction and 3D model generation.
* Optimizing scanning parameters for different types of biological tissues.

Main Results:

* Successful creation of detailed 3D digital models from micro-CT data.
* Visualization of complex internal micro-architectures within biological samples.
* Quantitative analysis of structural features from the generated models.

Conclusions:

* X-ray micro-computed tomography is a powerful tool for creating 3D models of biological samples.
* This technique enables comprehensive structural analysis without sample destruction.
* The described methods facilitate advanced research in biology and related fields.