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Neural Circuits: Reduced Inhibition in Fragile X Syndrome
Randall M Golovin1, Kendal Broadie2
1Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN 37232, USA.
Current Biology : CB
|April 26, 2017
Abstract:
The Drosophila Fragile X Syndrome model has long generated insights into this devastating neurological disease state. A recent study of olfactory neural circuitry shows that decreased lateral inhibition onto projection neurons relaying sensory input into higher brain centers causes impaired behavior.
