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Predictive equations for maximal respiratory pressures of children aged 7-10
George J da Rosa1, André M Morcillo2, Maíra S de Assumpção3
1Universidade do Estado de Santa Catarina (UDESC), Florianópolis, SC, Brazil.
Insights
New prediction equations for maximal respiratory pressures in children were developed for the Brazilian population. These equations, based on age and biometric data, aid in assessing respiratory muscle strength in pediatric patients.
Area of Science:
- Pediatric Pulmonology
- Respiratory Physiology
- Biostatistics
Background:
- Respiratory muscle strength assessment is crucial for pediatric evaluation.
- Existing predictive equations lack specificity for the Brazilian pediatric population.
- Establishing regional equations is essential for accurate clinical interpretation.
Purpose of the Study:
- To establish prediction equations for maximal respiratory pressures (maximal inspiratory pressure and maximal expiratory pressure) in healthy Brazilian children.
- To identify key demographic and biometric predictors for these pressures.
- To provide a normative reference for respiratory function in this cohort.
Main Methods:
- A cross-sectional observational study included 399 healthy children aged 7-10 years.
- Maximal respiratory pressures were measured following American Thoracic Society guidelines.
- Simple linear regression and multivariate analyses were used to develop predictive models, with age, weight, height, and BMI as potential predictors.
Main Results:
- Boys exhibited higher maximal respiratory pressures than girls, with both increasing with age.
- Moderate correlations were observed between respiratory pressures and age/biometric data in boys.
- In girls, maximal inspiratory pressure showed weak correlation with age, while maximal expiratory pressure correlated moderately with age and biometrics.
- Specific predictive models were derived for boys and girls, with R-squared values ranging from 13.9% to 21.6%.
Conclusions:
- Novel prediction equations for maximal respiratory pressures were successfully developed for Brazilian boys and girls.
- Biometric measurements demonstrated a relatively weak influence on the predictive models.
- These equations provide a valuable tool for assessing respiratory muscle strength in Brazilian children.
Background:
Measurements of respiratory muscle strength are widely used for assessment in children; however, clearly defined predictive equations for the Brazilian pediatric population have yet to be established.
Objective:
To determine the prediction equations for maximal respiratory pressures in healthy children.
Method:
Cross-sectional observational study with normal-weight students aged 7-10 years (n=399, 198 boys) with health attested by the (International Study of Asthma and Allergies in Childhood) questionnaire and medical history. Biometric data were evaluated (weight, height, and body mass index) as predictors. Spirometry and maximal expiratory pressure values were measured according to the recommendations of the American Thoracic Society. To verify data normality, the Shapiro-Wilk test was applied, and Pearson's test was used to verify the correlation between variables. The models were developed using simple linear regression and multivariate analyses. For all tests, the significance level was p<0.05.
Results:
Boys showed higher values of maximal respiratory pressures than girls, both increasing with age. For boys, these values had moderate correlation with age, weight, and height and weak correlation with body mass index. For girls, maximum inspiratory pressure had a weak correlation with age and moderate correlation with biometric data. Maximum expiratory pressure had a moderate correlation with age and biometric measures. The best predictive models were found in boys: Log(MIP)=1.577+0.006×weight (kg) (R2aj=14.1%) and Log(MEP)=1.282+0.409×height (m) (R2aj=13.9%); and for girls: Log(MIP)=1.548+0.006×weight (kg) (R2aj=15.0%) and Log(MEP)=1.524+0.012×age (years)+0.005×weight (kg) (R2aj=21.6%).
Conclusion:
Prediction equations for maximal respiratory pressures were developed for boys and girls. The biometric measurements were shown to have a weak influence on the results.
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