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Helicobacter pullorum: An Emerging Zoonotic Pathogen.

Sundus Javed1, Farzana Gul1, Kashaf Javed1

  • 1Department of BioSciences, COMSATS Institute of Information TechnologyIslamabad, Pakistan.

Frontiers in Microbiology
|April 27, 2017
PubMed
Summary

Helicobacter pullorum, a poultry bacterium, can infect humans, causing gastrointestinal issues. Further research is needed to understand its transmission and virulence factors for disease control.

Keywords:
H. pullorumHelicobacterenteric Helicobacter speciesfoodborne pathogenzoonotic pathogen

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Area of Science:

  • Veterinary Microbiology
  • Zoonotic Diseases
  • Food Safety

Background:

  • Helicobacter pullorum (H. pullorum) is prevalent in poultry, often causing gastroenteritis.
  • Human infections with H. pullorum are linked to colitis and hepatitis, transmitted via contaminated meat.
  • Limited knowledge exists regarding H. pullorum's infection mechanisms and virulence factors in hosts.

Purpose of the Study:

  • To provide a comprehensive overview of Helicobacter pullorum as an emerging zoonotic pathogen.
  • To detail H. pullorum's characteristics, hosts, prevalence, and transmission routes.
  • To discuss the pathogenic potential, control strategies, and disease emergence risks associated with H. pullorum.

Main Methods:

  • Literature review and synthesis of existing research on H. pullorum.
  • Analysis of epidemiological data on H. pullorum prevalence in poultry and humans.
  • Review of studies on H. pullorum's pathogenicity and virulence factors.

Main Results:

  • H. pullorum is a significant zoonotic agent with a notable presence in poultry populations.
  • Transmission to humans occurs through the food chain, particularly contaminated poultry meat.
  • The bacterium's pathogenic mechanisms and determinants require further elucidation.

Conclusions:

  • H. pullorum represents a growing public health concern due to its zoonotic potential.
  • Understanding H. pullorum's virulence is crucial for developing effective control and prevention strategies.
  • Continued surveillance and research are necessary to mitigate the risk of H. pullorum-associated diseases.