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Updated: Mar 3, 2026

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
Incidental Leydig Cell Tumor in Patient with Hormone Resistant Prostate Cancer
M Sánchez Pérez1, P Jiménez Marrero1, D Kim Lee1
1Servicio de Urología HUGCDN Barranco de la Ballena s/n Las Palmas de Gran Canaria, Spain.
Abstract:
We hereby present the case of a 55 years old patient with clinical diagnosis of high-risk prostate cancer T2bN1Mo Gleason 9 (4 + 5) treated with androgen deprivation therapy and external beam radiotherapy. Despite treatment, castration levels were not achieved and clinical progression was evidenced by the appearance of bone metastases and progression of PSA. After several hormonal treatments without any PSA or testosterone response, surgical castration was performed by bilateral orchiectomy. The pathology results showed an incidental Leydig cell tumor in the right testicle.

