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Updated: Mar 3, 2026
The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation
Published on: August 15, 2018
Towards evidence-based resuscitation of the newborn infant
Brett J Manley1, Louise S Owen2, Stuart B Hooper3
1Neonatal Services, The Royal Women's Hospital, Melbourne, VIC, Australia; Newborn Research Centre, The Royal Women's Hospital, Melbourne, VIC, Australia; Department of Obstetrics and Gynaecology, The University of Melbourne, Melbourne, VIC, Australia.
Insights
Effective newborn resuscitation saves lives and reduces disabilities from peripartum asphyxia. Advances include monitoring, avoiding hyperoxia, delayed cord clamping, and therapeutic hypothermia.
Area of Science:
- Neonatal Medicine
- Pediatric Resuscitation
- Perinatal Asphyxia
Background:
- Peripartum asphyxia poses significant risks to newborns, leading to mortality and long-term disabilities.
- Effective resuscitation strategies are crucial for improving neonatal outcomes globally.
Purpose of the Study:
- To review and highlight key advancements in newborn resuscitation techniques.
- To emphasize the importance of evidence-based practices in neonatal care.
Main Methods:
- Review of recent scientific literature and clinical trials on newborn resuscitation.
- Analysis of emerging monitoring techniques and therapeutic interventions.
Main Results:
- Monitoring techniques enhance the guidance of resuscitative efforts.
- Awareness of hyperoxia's adverse effects is critical.
- Delayed umbilical cord clamping and avoiding routine endotracheal intubation for extremely preterm infants are beneficial.
- Therapeutic hypothermia is effective for hypoxic-ischaemic encephalopathy.
Conclusions:
- Continuous research and clinical trials are refining effective newborn resuscitation.
- Implementing advanced techniques can significantly improve survival and reduce disabilities in affected infants.
Abstract:
Effective resuscitation of the newborn infant has the potential to save many lives around the world and reduce disabilities in children who survive peripartum asphyxia. In this Series paper, we highlight some of the important advances in the understanding of how best to resuscitate newborn infants, which includes monitoring techniques to guide resuscitative efforts, increasing awareness of the adverse effects of hyperoxia, delayed umbilical cord clamping, the avoidance of routine endotracheal intubation for extremely preterm infants, and therapeutic hypothermia for hypoxic-ischaemic encephalopathy. Despite the challenges of performing high-quality clinical research in the delivery room, researchers continue to refine and advance our knowledge of effective resuscitation of newborn infants through scientific experiments and clinical trials.
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