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Prognostic Factors in Severe Chagasic Heart Failure
Sandra de Araújo Costa1, Salvador Rassi1, Elis Marra da Madeira Freitas1
1Universidade Federal de Goiás, Goiânia, GO, Brazil.
Arquivos Brasileiros De Cardiologia
|April 27, 2017
Summary
Prognostic factors for severe Chagasic heart failure are identified. Non-sustained ventricular tachycardia and indexed left atrial volume independently predict mortality, with only 11% survival over 7.5 years.
Area of Science:
- Cardiology
- Tropical Medicine
- Public Health
Background:
- Prognostic factors are crucial in heart failure management.
- Limited data exists on prognostic factors in severe Chagasic heart failure.
Purpose of the Study:
- Identify clinical and laboratory factors associated with prognosis in severe Chagasic heart failure.
- Determine the association of these factors with mortality and survival over a 7.5-year follow-up period.
Main Methods:
- Evaluated 60 patients with severe Chagasic heart failure.
- Assessed variables including age, blood pressure, ejection fraction, serum sodium, creatinine, 6-minute walk test, non-sustained ventricular tachycardia, QRS width, indexed left atrial volume, and functional class.
Main Results:
- 88.3% of patients died during the 7.5-year follow-up, with an overall survival probability of approximately 11%.
- Non-sustained ventricular tachycardia (HR = 2.11) and indexed left atrial volume ≥ 72 mL/m2 (HR = 3.51) were identified as independent predictors of mortality.
Conclusions:
- Non-sustained ventricular tachycardia and indexed left atrial volume > 72 mL/m2 are independent predictors of mortality in severe Chagasic heart failure.
- These findings highlight the poor prognosis, with a cumulative survival probability of only 11% over 7.5 years.
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